The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes.

@article{Spycher2008TheMC,
  title={The Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes.},
  author={Cornelia Spycher and Melanie Rug and Esther Pachlatko and Eric Hanssen and David J. P. Ferguson and Alan F Cowman and Leann Tilley and H. Beck},
  journal={Molecular microbiology},
  year={2008},
  volume={68 5},
  pages={1300-14}
}
During the intra-erythrocytic development of Plasmodium falciparum, the parasite modifies the host cell surface by exporting proteins that interact with or insert into the erythrocyte membrane. These proteins include the principal mediator of cytoadherence, P. falciparum erythrocyte membrane protein 1 (PfEMP1). To implement these changes, the parasite establishes a protein-trafficking system beyond its confines. Membrane-bound structures called Maurer's clefts are intermediate trafficking… CONTINUE READING
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