The Marfan syndrome gene locus as a favoured locus for susceptibility to schizophrenia.

@article{Kalsi1994TheMS,
  title={The Marfan syndrome gene locus as a favoured locus for susceptibility to schizophrenia.},
  author={Gursharan Kalsi and Baljinder Singh Mankoo and Jon Brynjolfsson and David Curtis and Tara Read and Patrice R. Murphy and Tonmoy Sharma and Hannes Petursson and Hugh MD Gurling},
  journal={Psychiatric genetics},
  year={1994},
  volume={4 4},
  pages={
          219-27
        }
}
Marfan syndrome (MS) is a rare autosomal dominant disorder of connective tissue with manifestations in the cardiovascular, ocular and skeletal systems. Genetic linkage analysis with random probes has mapped the MS locus to 15q21.1. There have been several reports of Marfan syndrome co-segregating with schizophrenia within families, which suggest that a common genetic factor may be shared between schizophrenia susceptibility and MS. This could be due to a cytogenetic abnormality affecting both… CONTINUE READING

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NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees.

Charles A. Kaufmann, Brian K. Suarez, +15 authors C. Robert Cloninger
  • American journal of medical genetics
  • 1998
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