The Many Faces of Wnt and Pancreatic Ductal Adenocarcinoma Oncogenesis

Abstract

Pancreatic ductal adenocarcinoma (PDAC) remains amongst the most lethal human cancers. PDAC is characterized by the tumor mass containing a paucity of malignant cells in association with a large desmoplastic reaction comprised of a variety of stromal components. Sporadic PDAC oncogenesis occurs as a result of the sequential acquisition of genetic… (More)
DOI: 10.3390/cancers3033676

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