The Mammary Gland Microenvironment Directs Progenitor Cell Fate In Vivo

@inproceedings{Bussard2011TheMG,
  title={The Mammary Gland Microenvironment Directs Progenitor Cell Fate In Vivo},
  author={Karen M Bussard and Gilbert H Smith},
  booktitle={International journal of cell biology},
  year={2011}
}
The mammary gland is a unique organ that continually undergoes postnatal developmental changes. In mice, the mammary gland is formed via signals from terminal end buds, which direct ductal growth and elongation. Intriguingly, it is likely that the entire cellular repertoire of the mammary gland is formed from a single antecedent cell. Furthermore, in order to produce progeny of varied lineages (e.g., luminal and myoepithelial cells), signals from the local tissue microenvironment influence… CONTINUE READING

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