The Mammary Gland: A Model for Development

@article{Daniel2004TheMG,
  title={The Mammary Gland: A Model for Development},
  author={Charles W. Daniel and Gilbert H. Smith},
  journal={Journal of Mammary Gland Biology and Neoplasia},
  year={2004},
  volume={4},
  pages={3-8}
}
questions with broad biological implications for the Hennighausen and colleagues, in a recent review development of many organs and tissues in a variety (1) cite evidence that more than 8,300 publications on of organisms. Much of the emergence of the mammary the development and secretions of the mammary gland gland as a model system is due to powerful experimenhad been published by 1899. The term a development,o tal techniques that are uniquely available to pracwhen used in reference to mammary… 

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    Journal of Mammary Gland Biology and Neoplasia
  • 2005
Some unique properties of the mammary gland are illustrated which provide the basis for specialized approaches to developmental, neoplastic, and functional problems.

Think globally, act locally: the making of a mouse mammary gland.

On a phylogenetic scale of organ development the mammary gland is a recent acquisition. It was introduced 200 million years ago with the appearance of mammals to provide nourishment to the newborn in

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Together, these results indicate that progesterone acts by a paracrine mechanism on a subset of mammary epithelial cells to allow for alveolar growth and that expression of the PR is not required in all the cells of the Mammary epithelium in order forAlveolar development to proceed normally.

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