The Maillard protein cross-link pentosidine in urine from diabetic patients

@article{Takahashi1993TheMP,
  title={The Maillard protein cross-link pentosidine in urine from diabetic patients},
  author={M Takahashi and Tsuyoshi Ohishi and Hiroe Aoshima and Kouich Kawana and Kazuhiro Kushida and Tetsuo Inoue and Kazutaka Horiuchi},
  journal={Diabetologia},
  year={1993},
  volume={36},
  pages={664-667}
}
The Maillard protein cross-link pentosidine is a fluorescent condensation product of lysine, arginine and ribose. It accumulates in human tissues with age, and the accumulation process is accelerated in the tissues of diabetic patients. Using SP-Sephadex C-25 in the pretreatment for HPLC, we examined levels of pentosidine in urine without hydrolysis (free form) and levels of pentosidine in urine after hydrolysis (total forms), from 23 diabetic patients and 21 control subjects. The mean… CONTINUE READING