The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

Abstract

Membrane-associated guanylate kinase (Maguk) proteins are scaffold proteins that contain PSD-95-Discs Large-zona occludens-1 (PDZ), Src homology 3, and guanylate kinase domains. A subset of Maguk proteins, such as mLin-2 and protein associated with Lin-7 (Pals)1, also contain two L27 domains: an L27C domain that binds mLin-7 and an L27N domain of unknown… (More)

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Cite this paper

@article{Roh2002TheMP, title={The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost}, author={Michael H. Roh and Olga Makarova and Chia-jen Liu and Shin and Seonok Lee and Stephanie Laurinec and Meera Goyal and Roger C. Wiggins and Ben L. Margolis}, journal={The Journal of Cell Biology}, year={2002}, volume={157}, pages={161 - 172} }