The MYST family of histone acetyltransferases and their intimate links to cancer

@article{Avvakumov2007TheMF,
  title={The MYST family of histone acetyltransferases and their intimate links to cancer},
  author={Nikita Avvakumov and Jean-François C{\^o}t{\'e}},
  journal={Oncogene},
  year={2007},
  volume={26},
  pages={5395-5407}
}
The histone acetyltransferases (HATs) of the MYST family are highly conserved in eukaryotes and carry out a significant proportion of all nuclear acetylation. These enzymes function exclusively in multisubunit protein complexes whose composition is also evolutionarily conserved. MYST HATs are involved in a number of key nuclear processes and play critical roles in gene-specific transcription regulation, DNA damage response and repair, as well as DNA replication. This suggests that anomalous… CONTINUE READING

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