The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenase.

@article{Koslowsky1990TheMG,
  title={The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenase.},
  author={Donna Koslowsky and Ganapati J Bhat and A L Perrollaz and Jean E. Feagin and Kenneth Stuart},
  journal={Cell},
  year={1990},
  volume={62 5},
  pages={901-11}
}
Mitochondrial MURF3 transcripts of T. brucei are extensively edited by the addition and deletion of uridines. The editing creates potential initiation and termination codons and a continuous open reading frame. The predicted amino acid sequence has homology to a subunit of NADH dehydrogenase (ND7). ND7 is independently edited in two distinct domains, suggesting two editing initiation sites. Editing in the two domains is differentially regulated: the 5' domain is edited in both bloodstream and… CONTINUE READING

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