The MTRR 66A>G polymorphism and maternal risk of birth of a child with Down syndrome in Caucasian women: a case–control study and a meta-analysis

@article{Copped2014TheM6,
  title={The MTRR 66A>G polymorphism and maternal risk of birth of a child with Down syndrome in Caucasian women: a case–control study and a meta-analysis},
  author={Fabio Copped{\`e} and P. I. Bosco and Valentina Lorenzoni and Maria Denaro and Guido Anello and Ivana Antonucci and Concetta Barone and Liborio Stuppia and Corrado Romano and Lucia Migliore},
  journal={Molecular Biology Reports},
  year={2014},
  volume={41},
  pages={5571-5583}
}
We performed a large case–control study and a meta-analysis of the literature to address the role of the methionine synthase reductase (MTRR) c.66A>G polymorphism as a maternal risk factor for the birth of a child with Down Syndrome (DS) among Caucasian women. A total of 253 mothers of a DS child (MDS) and 298 control mothers of Italian origin were included in the case–control study. The meta-analysis of previous and present data involved a total of seven studies performed in Caucasian… CONTINUE READING
BETA

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Risk factors for Down syndrome

  • Archives of Toxicology
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Similar Papers

Loading similar papers…