The MTG proteins: chromatin repression players with a passion for networking.

@article{Rossetti2004TheMP,
  title={The MTG proteins: chromatin repression players with a passion for networking.},
  author={Stefano Rossetti and Andr{\'e} T. Hoogeveen and Nicoletta Sacchi},
  journal={Genomics},
  year={2004},
  volume={84 1},
  pages={
          1-9
        }
}
The human myeloid translocation genes (MTGs) encode a family of proteins with a modular structure that can be traced to the Drosophila protein nervy. The nuclear MTGs can mediate the formation of complex protein networks among nuclear corepressors (Sin3a, N-CoR, SMRT), chromatin-modifying enzymes (histone deacetylases), and DNA-binding transcription factors. Hierarchical modulation of repression at target genes by MTG protein complexes is likely required for fine spatial and temporal gene… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

Similar Papers

Loading similar papers…