The MMSE is not an adequate screening cognitive instrument in studies of late-life depression.

@article{Rajji2009TheMI,
  title={The MMSE is not an adequate screening cognitive instrument in studies of late-life depression.},
  author={Tarek K Rajji and D. Pereira de Miranda and Benoit H. Mulsant and Meredith J. Lotz and Patricia R. Houck and Michelle D Zmuda and Salem G Bensasi and Charles F. Reynolds and Meryl A. Butters},
  journal={Journal of psychiatric research},
  year={2009},
  volume={43 4},
  pages={464-70}
}
BACKGROUND The Mini Mental State Examination (MMSE) is frequently used to assess cognition in studies of late-life depression (LLD). However, its sensitivity and specificity in this population are largely unknown. We undertook an analysis of subjects with LLD and hypothesized that: (1) at the traditional cutoff of 24, the MMSE would have low sensitivity in the detection of cognitive impairment; (2) increasing the cutoff score would improve this sensitivity at the expense of a minimal reduction… CONTINUE READING

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