The MIA system for protein import into the mitochondrial intermembrane space.

@article{Stojanovski2008TheMS,
  title={The MIA system for protein import into the mitochondrial intermembrane space.},
  author={Diana Stojanovski and Judith M M{\"u}ller and Dusanka Milenkovic and Bernard Guiard and Nikolaus Pfanner and Agnieszka Chacinska},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1783 4},
  pages={610-7}
}
When thinking of the mitochondrial intermembrane space we envisage a small compartment that is bordered by the mitochondrial outer and inner membranes. Despite this somewhat simplified perception the intermembrane space has remained a central focus in mitochondrial biology. This compartment accommodates many proteinaceous factors that play critical roles in mitochondrial and cellular metabolism, including the regulation of programmed cell death and energy conversion. The mechanism by which… CONTINUE READING