The MCP/eotaxin subfamily of CC chemokines.

  title={The MCP/eotaxin subfamily of CC chemokines.},
  author={Els Van Coillie and Jo Van Damme and Ghislain Opdenakker},
  journal={Cytokine & growth factor reviews},
  volume={10 1},
Migration of leukocytes from the bone marrow to the circulation, the primary lymphoid organs and inflammatory sites is directed by chemokines and specific receptor interactions. Besides the role of this group of low molecular weight cytokines in leukocyte attraction and activation, anti-HIV and hematopoietic activities were also attributed to chemokines. On the basis of the number and arrangement of the conserved cysteines, chemokines are subdivided in two multi-member families, namely the CXC… CONTINUE READING


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