The MAPK signaling cascade

@article{Seger1995TheMS,
  title={The MAPK signaling cascade},
  author={Rony Seger and Edwin G. Krebs},
  journal={The FASEB Journal},
  year={1995},
  volume={9},
  pages={726 - 735}
}
The transmission of extracellular signals into their intracellular targets is mediated by a network of interacting proteins that regulate a large number of cellular processes. Cumulative efforts from many laboratories over the past decade have allowed the elucidation of one such signaling mechanism, which involves activations of several membranal signaling molecules followed by a sequential stimulation of several cytoplasmic protein kinases collectively known as mitogen‐activated protein kinase… 

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  • G. Fanger
  • Biology
    Histology and histopathology
  • 1999
This review describes what is currently known about the subcellular localization of MAPK pathway signaling proteins and the relocalization that occurs during events associated with activation of the MAPK family members.
...

References

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