The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching

@inproceedings{Jeanneteau2010TheMK,
  title={The MAP kinase phosphatase, MKP-1, regulates BDNF-induced axon branching},
  author={Freddy D Jeanneteau and Katrin Deinhardt and Goichi Miyoshi and Anton M Bennett and Moses V Chao},
  booktitle={Nature Neuroscience},
  year={2010}
}
The refinement of neural circuits during development depends on a dynamic process of branching of axons and dendrites that leads to synapse formation and connectivity. The neurotrophin brain-derived neurotrophic factor (BDNF) is essential for the outgrowth and activity-dependent remodeling of axonal arbors in vivo. However, the mechanisms that translate… CONTINUE READING