The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.

@article{Miranda2002TheMM,
  title={The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.},
  author={Claudia Miranda and Silvia Selleri and Marco Alessandro Pierotti and Angela Greco},
  journal={The Journal of investigative dermatology},
  year={2002},
  volume={119 4},
  pages={978-9}
}