The Ly6 neurotoxin-like molecule target of wit regulates spontaneous neurotransmitter release at the developing neuromuscular junction in Drosophila.

@article{Kim2012TheLN,
  title={The Ly6 neurotoxin-like molecule target of wit regulates spontaneous neurotransmitter release at the developing neuromuscular junction in Drosophila.},
  author={Nam Chul Kim and Guillermo Marqu{\'e}s},
  journal={Developmental neurobiology},
  year={2012},
  volume={72 12},
  pages={1541-58}
}
Refinement of neural circuits during development requires formation and elimination of synaptic connections, a process governed by activity-dependent mechanisms and developmental genetic programs. Bone Morphogenetic Protein (BMP) retrograde signaling through the type II receptor Wishful thinking (Wit) is essential for synaptic growth and functional development of the Drosophila larval neuromuscular junction. However, little is known about the genes that are regulated by the pathway to effect… CONTINUE READING
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