The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.

@article{Drevets2004TheLM,
  title={The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.},
  author={Douglas A. Drevets and Marilyn J. Dillon and Jennifer S Schawang and Nico Van Rooijen and Jan Ehrchen and Cord Sunderkoetter and Pieter Johannes Maria Leenen},
  journal={Journal of immunology},
  year={2004},
  volume={172 7},
  pages={4418-24}
}
Mononuclear phagocytes can be used by intracellular pathogens to disseminate throughout the host. In the bloodstream these cells are generically referred to as monocytes. However, blood monocytes are a heterogeneous population, and the exact identity of the leukocyte(s) relevant for microbial spreading is not known. Experiments reported in this study used Listeria monocytogenes-infected mice to establish the phenotype of parasitized blood leukocytes and to test their role in systemic… CONTINUE READING
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