The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.

@article{Schauder2001TheLF,
  title={The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.},
  author={Stephan Schauder and Kevan Shokat and Michael G. Surette and Bonnie L Bassler},
  journal={Molecular microbiology},
  year={2001},
  volume={41 2},
  pages={463-76}
}
Many bacteria control gene expression in response to cell population density, and this phenomenon is called quorum sensing. In Gram-negative bacteria, quorum sensing typically involves the production, release and detection of acylated homoserine lactone signalling molecules called autoinducers. Vibrio harveyi, a Gram-negative bioluminescent marine bacterium, regulates light production in response to two distinct autoinducers (AI-1 and AI-2). AI-1 is a homoserine lactone. The structure of AI-2… CONTINUE READING
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