The Lutein and Zeaxanthin in Pregnancy (L-ZIP) study—carotenoid supplementation during pregnancy: ocular and systemic effects—study protocol for a randomized controlled trial

@article{Addo2021TheLA,
  title={The Lutein and Zeaxanthin in Pregnancy (L-ZIP) study—carotenoid supplementation during pregnancy: ocular and systemic effects—study protocol for a randomized controlled trial},
  author={Emmanuel Kofi Addo and Aruna Gorusupudi and Susan Allman and Paul S. Bernstein},
  journal={Trials},
  year={2021},
  volume={22}
}
Background Lutein (L), zeaxanthin (Z), and meso -zeaxanthin (MZ), collectively called the macular pigment (MP), are dietary carotenoids that preferentially localize in the macula of the human eye. MP protects the macula from photo-oxidative damage and enhances visual function. Inadequate maternal intake of carotenoids, coupled with the placental transfer of maternal carotenoids to support fetal brain and retina development, potentially put mothers at risk of depletion systemically and in their… 

Potential roles of dietary zeaxanthin and lutein in macular health and function.

Lutein, zeaxanthin, and meso-zeaxanthin are three xanthophyll carotenoid pigments that selectively concentrate in the center of the retina. Humans cannot synthesize lutein and zeaxanthin, so these

Early Pediatric Benefit of Lutein for Maturing Eyes and Brain—An Overview

The anatomical development of the eye and the brain is reviewed, the presence and selective deposition of lutein in these organs during pregnancy and infancy is explored and, based on its functional characteristics, the latest available research on the beneficial role of lutesin in the pediatric population is presented.

Lutein as a Modulator of Oxidative Stress-Mediated Inflammatory Diseases

The current knowledge regarding the anti-inflammatory function of lutein against inflammatory diseases in various organs is discussed, including neurodegenerative disorders, eye diseases, diabetic retinopathy, osteoporosis, cardiovascular diseases, skin diseases, liver injury, obesity, and colon diseases.

Effect of Natural Antioxidants from Marigolds (Tagetes erecta L.) on the Oxidative Stability of Soybean Oil

In recent years, synthetic antioxidants that are widely used in foods have been shown to cause detrimental health effects, and there has been growing interest in antioxidants realised from natural

Nourishing Better Vision: The ARVO 2021 Mildred Weisenfeld Award Lecture

  • P. Bernstein
  • Medicine
    Investigative ophthalmology & visual science
  • 2022
This year’s Weisenfeld lecture was delivered pre-recorded, with 10 minutes of live questions moderated by Dr. Michael Redmond of the National Eye Institute, and approximately 1000 participants viewed this lecture during its appointed time slot.

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