The Loss of Smell in Persistent Allergic Rhinitis Is Improved by Levocetirizine due to Reduction of Nasal Inflammation but Not Nasal Congestion (the CIRANO Study)

@article{Guilemany2012TheLO,
  title={The Loss of Smell in Persistent Allergic Rhinitis Is Improved by Levocetirizine due to Reduction of Nasal Inflammation but Not Nasal Congestion (the CIRANO Study)},
  author={J. Guilemany and Alfons Garc{\'i}a-Pi{\~n}ero and I. Alobid and S. Centellas and F. Mari{\~n}o and A. Valero and M. Bernal-Sprekelsen and C. Picado and J. Mullol},
  journal={International Archives of Allergy and Immunology},
  year={2012},
  volume={158},
  pages={184 - 190}
}
  • J. Guilemany, Alfons García-Piñero, +6 authors J. Mullol
  • Published 2012
  • Biology, Medicine
  • International Archives of Allergy and Immunology
  • Background: Persistent allergic rhinitis (PER) has a moderate impact on the sense of smell, but no controlled study has reported the effect of antihistamines on the loss of smell in patients with PER. Methods: Patients with PER and subjective loss of the sense of smell (n = 27) were included in this pilot randomised, double-blind, placebo-controlled study. Nasal symptoms, nasal endoscopy, skin prick test, acoustic rhinometry, peak nasal inspiratory flow, nasal nitric oxide (nNO), and… CONTINUE READING
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