The Long Noncoding RNA IFNG-AS1 Promotes T Helper Type 1 Cells Response in Patients with Hashimoto’s Thyroiditis

@inproceedings{Peng2015TheLN,
  title={The Long Noncoding RNA IFNG-AS1 Promotes T Helper Type 1 Cells Response in Patients with Hashimoto’s Thyroiditis},
  author={Huiyong Peng and Yingzhao Liu and Jie Tian and Jie Ma and Xinyi Tang and Ke Rui and Xinyu Tian and Chaoming Mao and Liwei Lu and Huaxi Xu and Pengcheng Jiang and Shengjun Wang},
  booktitle={Scientific reports},
  year={2015}
}
The long noncoding (lnc) RNA-Ifng-AS1 plays an essential role in the transcription of the gene encoding IFN-γ by Th1 cells, and its human ortholog, IFNG-AS1, is expressed in human Th1 cells. However, IFNG-AS1 contributing to Th1 cells' response in Hashimoto's thyroiditis (HT) patients has not been reported. Twenty-eight HT patients and 20 healthy controls were enrolled in the study. The proportion of circulating Th1 cells and the level of T-bet, IFNG mRNA were increased in HT patients, the… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

LncRNAs on guard.

  • International immunopharmacology
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells

T Chiyomaru
  • J Biol Chem 289,
  • 2014