The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility.

@article{Marr2007TheLP,
  title={The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility.},
  author={Alexandra K Marr and Joerg Overhage and Manjeet Bains and Robert E. Hancock},
  journal={Microbiology},
  year={2007},
  volume={153 Pt 2},
  pages={474-82}
}
Pseudomonas aeruginosa is an important nosocomial opportunistic human pathogen and a major cause of chronic lung infections in individuals with cystic fibrosis. Serious infections by this organism are often treated with a combination of aminoglycosides and semi-synthetic penicillins. Subinhibitory concentrations of antibiotics are now being recognized for their role in microbial persistence and the development of antimicrobial resistance, two very important clinical phenomena. An extensive… CONTINUE READING

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