The Locomotor Effects of Quinpirole in Rats Depend on Age and Gender

@article{Frantz1999TheLE,
  title={The Locomotor Effects of Quinpirole in Rats Depend on Age and Gender},
  author={Kyle J. Frantz and C J Van Hartesveldt},
  journal={Pharmacology Biochemistry and Behavior},
  year={1999},
  volume={64},
  pages={821-826}
}
Periadolescence in the rat [postnatal day (PND) 35-50] is an important but understudied period of neurobehavioral development. In this experiment, an ongoing survey of the effects of quinpirole in developing rats was completed by the addition of periadolescent rats to the range of ages tested. PND40 or 50 rats were injected subcutaneously with the dopamine D2/D3 receptor agonist, quinpirole (0.0, 0.02, 0.2, or 2.0 mg/kg), and their locomotor activity was recorded. Periadolescent rats showed… CONTINUE READING

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