The Localization of Bullous Pemphigoid Antigen 180 (BP180) in Hemidesmosomes Is Mediated by Its Cytoplasmic Domain and Seems to be Regulated by the β4 Integrin Subunit

@article{Borradori1997TheLO,
  title={The Localization of Bullous Pemphigoid Antigen 180 (BP180) in Hemidesmosomes Is Mediated by Its Cytoplasmic Domain and Seems to be Regulated by the β4 Integrin Subunit},
  author={Luca Borradori and Peter J Koch and C. Niessen and Stefan J. Erkeland and Manuel R. van Leusden and Arnoud Sonnenberg},
  journal={The Journal of Cell Biology},
  year={1997},
  volume={136},
  pages={1333 - 1347}
}
Bullous pemphigoid antigen 180 (BP180) is a component of hemidesmosomes, i.e., cell-substrate adhesion complexes. To determine the function of specific sequences of BP180 to its incorporation in hemidesmosomes, we have transfected 804G cells with cDNA-constructs encoding wild-type and deletion mutant forms of human BP180. The results show that the cytoplasmic domain of BP180 contains sufficient information for the recruitment of the protein into hemidesmosomes because removal of the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

The subcellular distribution of the high molecular on F ebuary 21

  • P. Sanchez-Aparicio, A. M. Martinez de Velasco, +6 authors A. Sonnenberg
  • D ow nladed fom Published March
  • 1997

Similar Papers

Loading similar papers…