The Listeria transcriptional landscape from saprophytism to virulence

@article{ToledoArana2009TheLT,
  title={The Listeria transcriptional landscape from saprophytism to virulence},
  author={Alejandro Toledo-Arana and Olivier Dussurget and Georgios Nikitas and Nina Sesto and H{\'e}l{\`e}ne Guet-Revillet and Damien Balestrino and Edmund Loh and Jonas Gripenland and Teresa Tiensuu and Karolis Vaitkevicius and Mathieu Barth{\'e}lemy and Massimo Vergassola and M A Nahori and Guillaume Soubigou and B{\'e}atrice Regnault and Jean Yves Coppee and Marc Lecuit and J{\"o}rgen Johansson and Pascale Cossart},
  journal={Nature},
  year={2009},
  volume={459},
  pages={950-956}
}
The bacterium Listeria monocytogenes is ubiquitous in the environment and can lead to severe food-borne infections. It has recently emerged as a multifaceted model in pathogenesis. However, how this bacterium switches from a saprophyte to a pathogen is largely unknown. Here, using tiling arrays and RNAs from wild-type and mutant bacteria grown in vitro, ex vivo and in vivo, we have analysed the transcription of its entire genome. We provide the complete Listeria operon map and have uncovered… 
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