The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina.

Abstract

Retinal amacrine cells are a diverse set of interneurons within the inner nuclear layer. The canonical Wnt pathway is highly active within mature amacrine cells, but its role remains unclear. Leucine-rich repeat containing G-protein receptor 5 (Lgr5) is a newly identified component of the Wnt receptor complex that potentiates beta-catenin signaling. In… (More)
DOI: 10.1016/j.exer.2013.11.003

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