The Leu33/Pro polymorphism (PlA1/PlA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM Study. Etude Cas-Temoins de l'Infarctus du Myocarde.

@article{Herrmann1997TheLP,
  title={The Leu33/Pro polymorphism (PlA1/PlA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM Study. Etude Cas-Temoins de l'Infarctus du Myocarde.},
  author={S M Herrmann and Odette Poirier and Pedro M. Marques-Vidal and Alun E. Evans and Dominique Arveiler and G{\'e}rald Luc and Joseph Emmerich and François Cambien},
  journal={Thrombosis and haemostasis},
  year={1997},
  volume={77 6},
  pages={1179-81}
}
The GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlA1/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls. 

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