The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.


The activity of proteins delivered into host cells by the Dot/Icm injection apparatus allows Legionella pneumophila to establish a niche called the Legionella-containing vacuole (LCV), which is permissive for intracellular bacterial propagation. Among these proteins, substrate of Icm/Dot transporter (SidC) anchors to the cytoplasmic surface of the LCV and… (More)
DOI: 10.1073/pnas.1402605111


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