The Le(x) carbohydrate sequence is recognized by antibody to L5, a functional antigen in early neural development.

@article{Streit1996TheLC,
  title={The Le(x) carbohydrate sequence is recognized by antibody to L5, a functional antigen in early neural development.},
  author={Alexander Streit and C. T. Yuen and R. Wendy Loveless and Alexander M. Lawson and Jukka Finne and Brigitte Schmitz and Ten E N Feizi and Claudio D Stern},
  journal={Journal of neurochemistry},
  year={1996},
  volume={66 2},
  pages={834-44}
}
The L5 antigenic determinant was previously suggested to be a carbohydrate epitope present on murine cell recognition molecules in the developing brain and to be an early neural marker in the chick embryo. Here, we show that L5 immunoreactivity is associated with complex-type N-glycosidic oligosaccharides. To identify the carbohydrate structure recognized by the L5 antibody, we investigate its binding to N-linked oligosaccharides derived from L5 glycoproteins and to known glycans. Results of… CONTINUE READING

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