The LacI family protein GlyR3 co-regulates the celC operon and manB in Clostridium thermocellum

@article{Choi2017TheLF,
  title={The LacI family protein GlyR3 co-regulates the celC operon and manB in Clostridium thermocellum},
  author={Jinlyung Choi and Dawn M. Klingeman and Steven D. Brown and Chris D. Cox},
  journal={Biotechnology for Biofuels},
  year={2017},
  volume={10}
}
BackgroundClostridium thermocellum utilizes a wide variety of free and cellulosomal cellulases and accessory enzymes to hydrolyze polysaccharides present in complex substrates. To date only a few studies have unveiled the details by which the expression of these cellulases are regulated. Recent studies have described the auto regulation of the celC operon and determined that the celC–glyR3–licA gene cluster and nearby manB–celT gene cluster are co-transcribed as polycistronic mRNA.ResultsIn… 

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