The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: A tool for distinguishing necrotizing fasciitis from other soft tissue infections*

@article{Wong2004TheL,
  title={The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: A tool for distinguishing necrotizing fasciitis from other soft tissue infections*},
  author={Chin-Ho Wong and Lay Wai Khin and Kien-Seng Heng and Kok Chai Tan and C. O. Low},
  journal={Critical Care Medicine},
  year={2004},
  volume={32},
  pages={1535-1541}
}
OBJECTIVE Early operative debridement is a major determinant of outcome in necrotizing fasciitis. [] Key MethodDESIGN Retrospective observational study of patients divided into a developmental cohort (n = 314) and validation cohort (n = 140) SETTING Two teaching tertiary care hospitals. PATIENTS One hundred forty-five patients with necrotizing fasciitis and 309 patients with severe cellulitis or abscesses admitted to the participating hospitals. INTERVENTIONS None.
Validation of LRINEC (Laboratory Risk Indicators for Diagnosis of Necrotizing Fasciitis) Scoring System for the Diagnosis of Necrotizing Fasciitis
TLDR
The LRINEC score is an impressive diagnostic tool to distinguish necrotized fasciitis from other severe soft tissue infections, but it is not useful for early recognition of necrotizing fAsciitis.
Study of the effectiveness of laboratory risk indicator for necrotizing fasciitis scoring system in the diagnosis of necrotizing fasciitis among patients presenting with soft tissue infections
TLDR
LRINEC scoring system and clinical assessment should be used concurrently for diagnosing necrotizing fasciitis from other soft tissue infections and if found to have good predictive values, it would be a boon to developing countries like India where the mortality of the disease is high.
A study on role of laboratory risk indicator for necrotizing fasciitis score in necrotizing fasciitis
TLDR
Necrotizing fasciitis represents a group of highly lethal infection characterized by rapidly progressing inflammation and necrosis, thought to be the main cause of tissue pathology, systemic shock, septic shock, multiple organ failure and mortality.
Prospective Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for Necrotizing Fasciitis of the Extremities
TLDR
The Laboratory Risk Indicator for Necrotizing Fasciitis score may not be an accurate tool for necrotized fasciitis risk stratification and differentiation between severe cellulitis and necrotizing fAsciitis in the emergency department setting based on the authors' study.
Reliability of the Laboratory Risk Indicator for Necrotizing Fasciitis (Lrinec) Score for Early Diagnosis of Necrotizing Fasciitis
TLDR
The LRINEC score is an impressive diagnostic tool to differentiate between necrotizing fasciitis and other less severe soft tissue infections enabling prompt and appropriate treatment.
Necrotizing fasciitis: diagnostic and prognostic value of laboratory risk indicator for necrotizing fasciitis score
TLDR
Skin and soft tissue infections (SSTI) were first described in the Hippocratic era and they have variable etiology, clinical presentations and severity, and it is very important to diagnose the early change.
LRINEC: An Objective Scoring System as a tool for early diagnosis of Necrotizing Fasciitis
TLDR
LRINEC scoring system has a better positive predictive value in identifying the onset of necrotizing fasciitis and risk strategizing of the patients with severe soft tissue infections.
The Laboratory Risk Indicator for Necrotizing Fasciitis score for discernment of necrotizing fasciitis originated from Vibrio vulnificus infections
TLDR
It is demonstrated that the LRINEC score and hemorrhagic bullous/blistering lesions are significant predictors of NF in patients with V. vulnificus–related SSTI.
Correlation of the laboratory risk indicators for necrotizing fasciitis (LRINEC) score with the clinical features and surgical management of necrotizing soft tissue infections
TLDR
The LRINEC score is a robust score capable of detecting even clinically early cases of necrotizing fasciitis, and its utility in early surgical management of NSTI is demonstrated.
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Necrotizing Fasciitis: Improved Survival With Early Recognition by Tissue Biopsy and Aggressive Surgical Treatment
TLDR
Frozen section tissue biopsy is a useful adjunct in establishing an early, accurate diagnosis of infectious gangrene in patients whose biopsy did not reveal necrotizing fasciitis.
Determinants of mortality for necrotizing soft-tissue infections.
TLDR
Early debridement of NSTi was associated with a significant decrease in mortality, and S. pyogenes infection was the most common cause of monomicrobial NSTI, but was not associated with an increased mortality.
Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study.
TLDR
Early recognition and expeditious initial wide excision and debridement along with appropriate antibiotic coverage and support of systemic effects of necrotizing fasciitis serve to decrease morbidity and mortality.
Necrotizing soft tissue infections. Risk factors for mortality and strategies for management.
TLDR
Necrotizing soft tissue infections represent a group of highly lethal infections best treated by early and repeated extensive debridement and broad-spectrum antibiotics and Hyperbaric oxygen appears to offer the advantage of early wound closure.
Necrotizing fasciitis: CT characteristics.
TLDR
CT criteria of asymmetric fascial thickening and gas are valuable in assessing suspected necrotizing fasciitis and CT also can provide information on coexistent deep collections.
Early recognition of potentially fatal necrotizing fasciitis. The use of frozen-section biopsy.
TLDR
It is indicated that rapid performance of frozen-section soft-tissue biopsy early in the evolution of a suspect lesion may provide a definitive and life-saving diagnosis of necrotizing fasciitis.
Necrotizing Soft-Tissue Infections
&NA; Necrotizing fasciitis is a rare and often fatal soft-tissue infection involving the superficial fascial layers of the extremities, abdomen, or perineum. Necrotizing fasciitis typically begins
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