The LPI/GPR55 axis enhances human breast cancer cell migration via HBXIP and p-MLC signaling

@article{Zhou2018TheLA,
  title={The LPI/GPR55 axis enhances human breast cancer cell migration via HBXIP and p-MLC signaling},
  author={Xiaolei Zhou and Xin Guo and Yu-pin Song and Chong-yue Zhu and Wei Zou},
  journal={Acta Pharmacologica Sinica},
  year={2018},
  volume={39},
  pages={459-471}
}
The G protein-coupled receptor 55 (GPR55) is expressed in multiple tissues, and has been implicated in cancer pathogenesis, but little is known about its role in the migratory behavior of cancer cells, particularly breast cancer cells. In this study we first showed that GPR55 expression levels in 38 metastatic lymph nodes of breast cancer patients were profoundly elevated, and were positively associated in human breast cancer cells with their migratory ability. Moreover, the plasma levels of… 
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