The LLT1 receptor induces IFN-gamma production by human natural killer cells.

@article{Mathew2004TheLR,
  title={The LLT1 receptor induces IFN-gamma production by human natural killer cells.},
  author={Porunelloor A Mathew and Samuel S. Chuang and Swapnil V. Vaidya and Pappanaicken R. Kumaresan and Kent S. Boles and Hoang-Tuan K Pham},
  journal={Molecular immunology},
  year={2004},
  volume={40 16},
  pages={1157-63}
}
Natural killer cell functions are regulated by signals through activating and inhibitory receptors. These receptors belong to the immunoglobulin superfamily or the lectin superfamily. We have previously identified a lectin-like transcript, LLT1, expressed in human NK cells. In the present study, we have generated a monoclonal antibody, L9.7, that specifically binds LLT1 receptor and studied the functional role of LLT1 in human NK cells. Binding of mAb L9.7 to surface LLT1 induced IFN-gamma… CONTINUE READING

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