The LIM class homeobox gene lim5: implied role in CNS patterning in Xenopus and zebrafish.

@article{Toyama1995TheLC,
  title={The LIM class homeobox gene lim5: implied role in CNS patterning in Xenopus and zebrafish.},
  author={Reiko Toyama and P E Curtiss and Hiroki Otani and Mikio Kimura and Igor B Dawid and Masanori Taira},
  journal={Developmental biology},
  year={1995},
  volume={170 2},
  pages={583-93}
}
LIM homeobox genes are characterized by encoding proteins in which two cysteine-rich LIM domains are associated with a homeodomain. We report the isolation of a gene, named Xlim-5 in Xenopus and lim5 in the zebrafish, that is highly similar in sequence but quite distinct in expression pattern from the previously described Xlim-1/lim1 gene. In both species studied the lim5 gene is expressed in the entire ectoderm in the early gastrula embryo. The Xlim-5 gene is activated in a cell autonomous… CONTINUE READING

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