The LC-MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome.

@article{Lemonakis2017TheLM,
  title={The LC-MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome.},
  author={Nikolaos Lemonakis and Hemant Poudyal and Maria Halabalaki and Lindsay Brown and Anthony Tsarbopoulos and A L Skaltsounis and Evagelos Gikas},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2017},
  volume={1041-1042},
  pages={45-59}
}
Hydroxytyrosol (HT), an important component of olive fruit and olive oil, improves the signs of metabolic syndrome in rats following chronic treatment. At a dose of 20mg/kg/day, HT decreased adiposity and improved cardiovascular and liver structure and function in rats fed with a high-carbohydrate, high-fat diet. An untargeted metabolomics approach has been… CONTINUE READING