The L6 membrane proteins--a new four-transmembrane superfamily.

  title={The L6 membrane proteins--a new four-transmembrane superfamily.},
  author={Mark D Wright and Jing Ni and George B. Rudy},
  journal={Protein science : a publication of the Protein Society},
  volume={9 8},
L6, IL-TMP, and TM4SF5 are cell surface proteins predicted to have four transmembrane domains. Previous sequence analysis led to their assignment as members of the tetraspanin superfamily. In this paper, we identify a new sequence (L6D) that is strikingly similar to L6, IL-TMP, and TM4SF5. Analyses of these four sequences indicate that they are not significantly related to genuine tetraspanins, but instead constitute their own L6 superfamily. 

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