The Kinetics of Microtubule Assembly

  title={The Kinetics of Microtubule Assembly},
  author={William A. Voter and Harold P Erickson},
A model describing the nucleation and assembly of purified tubulin has been developed. The novel feature of this model is a two stage nucleation process to allow the explicit inclusion of the two-dimensional nature of the early stages of microtubule assembly. In actin assembly the small starting nucleus has only one site for subunit addition as the two-stranded helix is formed. In contrast, microtubule assembly begins with the formation of a small two-dimensional section of microtubule wall… CONTINUE READING


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