The Kidney Early Evaluation Program (KEEP): program design and demographic characteristics of the population.

@article{Jurkovitz2008TheKE,
  title={The Kidney Early Evaluation Program (KEEP): program design and demographic characteristics of the population.},
  author={Claudine Jurkovitz and Yang Qiu and Changchun Wang and David T. Gilbertson and Wendy Weinstock Brown},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2008},
  volume={51 4 Suppl 2},
  pages={
          S3-12
        }
}
  • C. Jurkovitz, Yang Qiu, +2 authors W. Brown
  • Published 1 April 2008
  • Medicine
  • American journal of kidney diseases : the official journal of the National Kidney Foundation
BACKGROUND Chronic kidney disease (CKD) recently was identified as a public health problem requiring a public health prevention approach. The National Kidney Foundation Kidney Early Evaluation Program (KEEP), initiated in 2000, meets the definition of a public health program, offering surveillance and early detection of CKD. This report aims to detail demographic characteristics of KEEP participants and compare them with characteristics of participants in the National Health and Nutrition… 
Hypertension in early-stage kidney disease: an update from the Kidney Early Evaluation Program (KEEP).
TLDR
In the volunteer KEEP population, rates of hypertension and CKD were greater than in NHANES, most prominently in African Americans and participants with increased cardiovascular risk.
Hypertension and CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES), 1999-2004.
TLDR
Although distributions of hypertension were similar between databases, KEEP participants with cardiovascular risk factors have a greater prevalence of hypertension than similar NHANES participants, and study group participants younger than 46 years were more likely to have achieved goal blood pressure.
CKD in the United States: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.
TLDR
The targeted nature of the KEEP screening program and the large sample size with clinical characteristics comparable to NHANES validates KEEP as a valuable cohort to explore health associations for the CKD and at-risk-for-CKD populations in the United States.
Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004.
TLDR
The prevalence of diabetes in KEEP progressively increased with increasing stage of CKD, and this relationship persisted in subgroup analyses of older participants (age > 46 years), as well as in analyses stratified by sex, race, and other CKD risk factors.
Prevalence and associations of anemia of CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.
TLDR
Anemia was twice as common in the targeted KEEP chronic kidney disease screening program cohort than in the NHANES sample population, and African Americans had a 3-fold increased likelihood of anemia compared with whites.
Participant follow-up in the Kidney Early Evaluation Program (KEEP) after initial detection.
TLDR
The KEEP detection program with disease education appears to motivate the targeted population to seek physician care for CKD, and longer term follow-up is needed to determine whether detection and physician follow- up lead to changes in care and outcomes that may affect the increased risk of death, end-stage renal disease, or cardiovascular events.
CKD and cardiovascular disease in screened high-risk volunteer and general populations: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.
TLDR
CKD is independently associated with myocardial infarction or stroke in participants in a voluntary screening program and a randomly selected survey population, which was associated with increased short-term mortality in KEEP.
Physician utilization, risk-factor control, and CKD progression among participants in the Kidney Early Evaluation Program (KEEP).
TLDR
Control of cardiovascular risk factors is poor in the KEEP population, and the percentage of participants seeing a nephrologist is low, although better after the first screening.
Trends in mineral metabolism: Kidney Early Evaluation Program (KEEP) and the National Health and Nutrition Examination Survey (NHANES) 1999-2004.
TLDR
In a community-based CKD screening population, increased PTH level occurs early in patients with stage 3, typically with normal calcium and phosphorus levels, supported by cross-sectional analysis of calcium, phosphorus, and parathyroid hormone data from November 1, 2005, to December 31, 2006.
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