The Kety-Schmidt technique for repeated measurements of global cerebral blood flow and metabolism in the conscious rat.

@article{Linde1999TheKT,
  title={The Kety-Schmidt technique for repeated measurements of global cerebral blood flow and metabolism in the conscious rat.},
  author={Rasmus Linde and Ina K Schmalbruch and Olaf Bjarne Paulson and Peter L Madsen},
  journal={Acta physiologica Scandinavica},
  year={1999},
  volume={165 4},
  pages={395-401}
}
Cerebral activation will increase cerebral blood flow (CBF) and cerebral glucose uptake (CMRglc) more than it increases cerebral uptake of oxygen (CMR(O2)). To study this phenomenon, we present an application of the Kety-Schmidt technique that enables repetitive simultaneous determination of CBF, CMR(O2), CMRglc and CMRlac on awake, non-stressed animals. After constant intravenous infusion with 133Xenon, tracer infusion is terminated, and systemic arterial blood and cerebral venous blood are… CONTINUE READING

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