The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients

@article{Decker1996TheKS,
  title={The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients},
  author={Lisa L. Decker and Premlata Shankar and Ghazala H. Khan and Richard B. Freeman and Bruce J. Dezube and Judy Lieberman and David Thorley-Lawson},
  journal={The Journal of Experimental Medicine},
  year={1996},
  volume={184},
  pages={283 - 288}
}
Short DNA sequences have been identified, originally in association with Kaposi's sarcoma (KS) biopsies, that are highly homologous to oncogenic, lymphotropic herpesviruses. Recently a virus, Kaposi sarcoma associated herpesvirus (KSHV) or human herpesvirus-8 (HHV-8), bearing these sequences has been identified in a cell line derived from a body cavity-based lymphoma. In this report, we show that the same sequences are present in KS biopsies as DNA molecules of a form and size characteristic of… CONTINUE READING

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Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals

  • L. L. Decker, L. D. Klaman, D.A
  • Thorley-Lawson
  • 1996

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