The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

Abstract

The KDM5 family of histone demethylases removes the H3K4 tri-methylation (H3K4me3) mark frequently found at promoter regions of actively transcribed genes and is therefore generally considered to contribute to corepression. In this study, we show that knockdown (KD) of all expressed members of the KDM5 family in white and brown preadipocytes leads to… (More)
DOI: 10.1093/nar/gkw1156

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