The K-loop, a general feature of the Pyrococcus C/D guide RNAs, is an RNA structural motif related to the K-turn

@article{Nolivos2005TheKA,
  title={The K-loop, a general feature of the Pyrococcus C/D guide RNAs, is an RNA structural motif related to the K-turn},
  author={Sophie Nolivos and Agamemnon J. Carpousis and B{\'e}atrice Clouet-d'Orval},
  journal={Nucleic Acids Research},
  year={2005},
  volume={33},
  pages={6507 - 6514}
}
The C/D guide RNAs predicted from the genomic sequences of three species of Pyrococcus delineate a family of small non-coding archaeal RNAs involved in the methylation of rRNA and tRNA. The C/D guides assemble into ribonucleoprotein (RNP) that contains the methyltransferase. The protein L7Ae, a key structural component of the RNP, binds to a Kink-turn (K-turn) formed by the C/D motif. The K-turn is a structure that consists of two RNA stems separated by a short asymmetric loop with a… CONTINUE READING