The Jupiter study, CRP screening, and aggressive statin therapy-implications for the primary prevention of cardiovascular disease.

@article{Kones2009TheJS,
  title={The Jupiter study, CRP screening, and aggressive statin therapy-implications for the primary prevention of cardiovascular disease.},
  author={Richard Kones},
  journal={Therapeutic advances in cardiovascular disease},
  year={2009},
  volume={3 4},
  pages={309-15}
}
CRP levels are strong, independent predictors of cardiovascular risk and can enhance risk stratification. Jupiter enrolled 17 802 apparently healthy middle-aged men and women with CRP levels over 2.0 mg/l, and LDL less than 130 mg/dl. They were randomized to receive rosuvastatin 20 mg daily or placebo, and followed for a primary endpoint of nonfatal myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or cardiovascular death for 1.9 years. Rosuvastatin… CONTINUE READING
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