The Joint Effect of hOGG1, APE1, and ADPRT Polymorphisms and Cooking Oil Fumes on the Risk of Lung Adenocarcinoma in Chinese Non-Smoking Females

@inproceedings{Xue2013TheJE,
  title={The Joint Effect of hOGG1, APE1, and ADPRT Polymorphisms and Cooking Oil Fumes on the Risk of Lung Adenocarcinoma in Chinese Non-Smoking Females},
  author={Xiaoxia Xue and Zhihua Yin and Yao Lu and Haibo Zhang and Ying Yan and Yuxia Zhao and Xuelian Li and Zeshi Cui and Miao Yu and Lu Yao and Bao Sen Zhou},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND The human 8-oxoguanine DNA glycosylase 1 (hOGG1), apurinic/apyrimidinic endonuclease 1 (APE1), and adenosine diphosphate ribosyl transferase (ADPRT) genes play an important role in the DNA base excision repair pathway. Single nucleotide polymorphisms (SNPs) in critical genes are suspected to be associated with the risk of lung cancer. This study aimed to identify the association between the polymorphisms of hOGG1 Ser326Cys, APE1 Asp148Glu, and ADPRT Val762Ala, and the risk of lung… CONTINUE READING