The Janus kinases (Jaks)


The Janus kinase (Jak) family is one of ten recognized families of non-receptor tyrosine kinases. Mammals have four members of this family, Jak1, Jak2, Jak3 and Tyrosine kinase 2 (Tyk2). Birds, fish and insects also have Jaks. Each protein has a kinase domain and a catalytically inactive pseudo-kinase domain, and they each bind cytokine receptors through… (More)
DOI: 10.1186/gb-2004-5-12-253


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@article{Yamaoka2004TheJK, title={The Janus kinases (Jaks)}, author={Kunihiro Yamaoka and Pipsa Saharinen and Marko Pesu and Vance ET Holt and Olli Silvennoinen and John J O'Shea}, journal={Genome Biology}, year={2004}, volume={5}, pages={253 - 253} }