The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain.

@article{Eldik2003TheJF,
  title={The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain.},
  author={Linda J. Van Eldik and Mark S Wainwright},
  journal={Restorative neurology and neuroscience},
  year={2003},
  volume={21 3-4},
  pages={97-108}
}
Glia play active and vital roles in the CNS, including regulation of brain development, maintenance of cellular homeostasis and reparative responses to acute and chronic neurologic insults. However, in pathological conditions, glial function may be dysregulated resulting in enhanced neuroinflammation and further neurologic injury. The fundamental concept that aberrant regulation of a normally beneficial process may instead result in pathology is exemplified by the properties of the glial… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 124 extracted citations

Danger signals in trauma

European Journal of Trauma and Emergency Surgery • 2018
View 1 Excerpt

Similar Papers

Loading similar papers…