The JR blood group system: identification of alleles that alter expression.

@article{HueRoye2013TheJB,
  title={The JR blood group system: identification of alleles that alter expression.},
  author={Kim Hue-Roye and T Zelinski and Adam Cobaugh and Christine Lomas-Francis and Toru Miyazaki and Yoshihiko Tani and Connie M. Westhoff and Marion E. Reid},
  journal={Transfusion},
  year={2013},
  volume={53 11},
  pages={2710-4}
}
BACKGROUND The ABCG2 gene encodes antigens of the JR blood group system. Red blood cells (RBCs) from individuals homozygous for ABCG2 null alleles are nonreactive with polyclonal and monoclonal anti-Jr(a) . However, some RBCs have been defined as Jr(a+(W) /-) or Jr(a-), particularly when tested with polyclonal anti-Jr(a) . In an effort to resolve these apparent serologic ambiguities, the current study was undertaken. STUDY DESIGN AND METHODS Hemagglutination of RBCs from two individuals known… CONTINUE READING

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