The JAK2 V617F mutation is detectable in granulocyte populations at greater than two copies per cell among individuals with myeloproliferative disorders

@article{Hammond2007TheJV,
  title={The JAK2 V617F mutation is detectable in granulocyte populations at greater than two copies per cell among individuals with myeloproliferative disorders},
  author={Emma L Hammond and Kerry L Shaw and Richard Herrmann},
  journal={Leukemia},
  year={2007},
  volume={21},
  pages={815-816}
}
separation and detection with capillary electrophoresis and this test has a sensitivity up to 200 pg mutated DNA; they only sequenced selected cases. The method used has the same sensitivity as our method (allele-specific pcr), but the result is displayed by capillary electrophoresis instead of agarose gel electrophoresis. This study confirms our previous… CONTINUE READING